I have been a Frontpage users for many years. Although I started with Dreamweaver I moved back to Frontpage 2002. I just liked how it handled tables and formatted text more easily. I don't do web design extensively, you can tell because I am talking about tables instead of div's, but for what I do I have really enjoyed Expression Web.
One of the things I really like about it is how much easier using CSS to layout your site is with the new product. Also, the interface with ASP.Net apps is much better...although far from perfect. Since VS 2005 has a horrible visual design UI when it comes to web forms, I typically use Expression Web to do most of the layout and then VS for the coding. Also, EW has a toolbar section for the typical asp.net controls so you can even layout some of those things easily.
Thoughts?